Is Alka Seltzer bad for you? Is It Worth Trying?

Alka Seltzer is a popular antacid and pain reliever used by many people to alleviate symptoms such as heartburn, indigestion, and headache. However, concerns have been raised about the potential negative health effects of the medication, particularly with prolonged or excessive use.

In this article, we will delve into the ingredients and nutritional facts of Alka Seltzer, examine the possible health benefits and risks associated with its use, and provide expert opinions and studies to help determine if Alka Seltzer is bad for you.

What is Alka Seltzer?

Alka Seltzer is a brand name for a range of over-the-counter antacid and pain relief medications. It is typically used to relieve symptoms of heartburn, acid indigestion, and headache. 

Alka Seltzer is manufactured by Bayer Consumer Health, and is available in a variety of forms, including tablets, capsules, and effervescent tablets that dissolve in water. 

The active ingredients in Alka Seltzer vary depending on the specific product, but typically include aspirin, citric acid, and sodium bicarbonate.

Nutrition Facts of Alka Seltzer

Alka-Seltzer is primarily used to relieve symptoms associated with indigestion, heartburn, and upset stomach. As such, it does not have a nutritional label or ingredients in the same way that foods or drinks do. However, Alka-Seltzer contains the following active ingredients:

  1. Aspirin: Alka-Seltzer Original and Extra Strength varieties contain 325mg of aspirin per tablet. Aspirin is a non-steroidal anti-inflammatory drug (NSAID) that can help reduce pain, inflammation, and fever.
  2. Sodium bicarbonate: All Alka-Seltzer varieties contain sodium bicarbonate, which helps to neutralize stomach acid.
  3. Citric acid: Citric acid is also found in all Alka-Seltzer varieties, and it helps to enhance the effervescence and bubbling effect of the tablets when they are dissolved in water.
  4. Additional ingredients: Some Alka-Seltzer varieties may also contain other active ingredients, such as antacids or pain relievers, depending on the specific product.

It’s important to note that individuals with certain health conditions, such as high blood pressure or kidney disease, may need to limit their intake of sodium and therefore should consult with their healthcare provider before using Alka-Seltzer.

Pros and Cons

As a medication, Alka Seltzer is designed to provide relief from symptoms such as heartburn, acid indigestion, and upset stomach. Here are some potential pros and cons of using Alka Seltzer:



  • May cause side effects: Some people may experience side effects such as stomach pain, constipation, or diarrhea after taking Alka Seltzer.
  • May interact with other medications: Alka Seltzer may interact with certain prescription medications, so it’s important to talk to a doctor or pharmacist before taking it.
  • Not suitable for long-term use: Alka Seltzer is designed to provide temporary relief from symptoms and should not be used as a long-term solution for digestive issues.

It’s important to note that the specific pros and cons of using Alka Seltzer may vary depending on individual factors such as medical history, allergies, and other medications being taken. It’s always a good idea to talk to a doctor or pharmacist before using any medication.

Health Benefits of Alka Seltzer

Alka-Seltzer is primarily used as an antacid and pain reliever. It works by neutralizing stomach acid and reducing inflammation, providing relief from heartburn, acid indigestion, and upset stomach.

Here are some potential health benefits of Alka-Seltzer:

  1. Provides relief from heartburn: Alka-Seltzer’s antacid properties can provide relief from heartburn and acid indigestion. According to a study published in the journal Current Medical Research and Opinion, Alka-Seltzer was found to be effective in treating heartburn symptoms in patients with gastroesophageal reflux disease (GERD).
  2. Reduces inflammation: Alka-Seltzer contains aspirin, which has anti-inflammatory properties. According to a study published in the journal American Family Physician, aspirin has been shown to reduce inflammation in conditions such as rheumatoid arthritis and osteoarthritis.
  3. Relieves pain: Alka-Seltzer’s aspirin content can also provide relief from mild to moderate pain. Aspirin has been shown to be effective in relieving pain from conditions such as headaches, menstrual cramps, and toothaches.

It is important to note that while Alka-Seltzer can provide relief from symptoms, it is not a cure for underlying health conditions. It should only be used as directed and under the guidance of a healthcare professional.

What do Health experts say about Alka Seltzer?

Medical experts generally agree that Alka Seltzer is safe when used as directed for its intended purposes, which include relief from heartburn, acid indigestion, and headaches.

However, like any medication, there can be risks associated with improper use or misuse. It is important to always follow the instructions on the label and consult with a healthcare professional if you have any concerns or questions.

Who Should Avoid Alka Seltzer?

Alka-Seltzer is generally considered safe for most people to use, but there are some individuals who should avoid or limit its use. 

People with certain medical conditions, such as kidney disease or high blood pressure, may need to avoid or limit their intake of sodium bicarbonate, which is one of the main active ingredients in Alka-Seltzer. 

Additionally, individuals who are allergic to aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) should avoid Alka-Seltzer products that contain aspirin.

The American Heart Association recommends that people with high blood pressure or who are at risk for developing high blood pressure should limit their intake of sodium to no more than 2,300 milligrams per day. 

Since each tablet of Alka-Seltzer Original contains 324 milligrams of sodium, individuals with high blood pressure may need to limit their intake of Alka-Seltzer to avoid exceeding their recommended daily sodium intake.

Alternatives to Alka Seltzer

Some alternatives to Alka Seltzer for heartburn and indigestion relief are:

  1. Tums: Tums are a brand of antacid that can quickly neutralize stomach acid and provide relief from heartburn. They come in different flavors and can be chewed or swallowed whole.
  2. Pepto-Bismol: Pepto-Bismol is a medication that contains bismuth subsalicylate, which can help relieve symptoms of heartburn, indigestion, and upset stomach. It is available in liquid or chewable tablet form.
  3. Zantac: Zantac is an H2 blocker that can reduce the production of stomach acid and provide relief from heartburn and acid reflux. It comes in tablet or liquid form and is available over-the-counter or by prescription.

As with any medication or supplement, it’s important to talk to a healthcare provider before using an alternative to Alka Seltzer to make sure it is safe and appropriate for your individual needs.


Can Alka Seltzer be taken with other medications?

It’s important to consult with a doctor or pharmacist before taking Alka Seltzer with other medications to avoid possible drug interactions.

Is Alka Seltzer safe for pregnant women?

Pregnant women should consult with a doctor before taking Alka Seltzer to determine if it is safe for them to use during pregnancy.

How often can I take Alka Seltzer?

The recommended dosage of Alka Seltzer is no more than 4 tablets in 24 hours, and no more than 3 tablets in 24 hours if you are over 60 years of age.

Can Alka Seltzer be taken with food?

Alka Seltzer can be taken with or without food, but taking it with food may help to reduce stomach upset.

Can Alka Seltzer help with hangovers?

Alka Seltzer may help to relieve some symptoms of a hangover, such as headache and upset stomach. However, it is not a cure for a hangover and should not be relied upon as a substitute for drinking responsibly.

Conclusion: Is Alka Seltzer bad for you?

Alka Seltzer is a medication commonly used to alleviate symptoms of acid reflux, indigestion, and other related conditions. 

While it is generally considered safe for most people to use, it may not be suitable for individuals with certain medical conditions or those taking specific medications. Additionally, prolonged or excessive use of Alka Seltzer can lead to potential side effects. 

It is always recommended to consult a healthcare provider before starting any new medication or treatment. Therefore, Alka Seltzer is not necessarily bad for you if used properly and according to instructions, but it is important to use caution and seek professional advice if you have any concerns.


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9.        Kaplan S, Kaplan A, Marcoe K, Sauvage LR. Ticlopidine, Alka-Seltzer®, or a combination of Citric Acid with Aspirin: Effects on Platelet Aggregation in individuals with an insufficient response to Aspirin alone. Clinical and Applied Thrombosis/Hemostasis. 2000;6(4):222-225.

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  • Marixie Manarang, MT, undergrad MD

    Marixie Manarang is licensed Medical Laboratory Scientist and an undergraduate of Doctor of Medicine (MD). For one year, she completed her internship training in a government hospital, primarily catering to retired veterans and their dependents. Through her preceptorships in medical school, she gained exposure to patients from various medical departments. Marixie’s passion for writing stems from her excellent medical background, being a mother, and a strong desire to assist the elderly and others in need. Education: Our Lady of Fatima University Doctor of Medicine (MD), Doctor of Medicine (2012-2015), Angeles University Foundation Doctor of Medicine (MD), Doctor of Medicine (2009-2011), Angeles University Foundation Bachelors, Medical Technology (2004-2009)






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